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Vol.61 No.5 contents

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- Case Report -

A Case of Collision Cancer of the Lung Consisting of Invasive Mucinous Adenocarcinoma and Squamous Cell Carcinoma

Yoshifumi Shimada^1,2, Yoshinori Doki², Masataka Segawa², Takahiro Honma¹, Keitarou Tanabe¹, Katsuhiko Saitou³, Naoki Yoshimura^1
1Department of Thoracic and Cardiovascular Surgery, University of Toyama, Japan, ²Department of Chest Surgery, ³Department of Diagnostic Pathology, Toyama City Hospital, Japan

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Background. We herein report a rare case of primary pulmonary collision cancer comprising invasive mucinous adenocarcinoma (IMA) and squamous cell carcinoma (SCC). Case. A 77-year-old male patient with a chief complaint of coughing was referred to our hospital. Chest computed tomography (CT) revealed a massive infiltrating shadow in the right lower lobe. The tumor was diagnosed as adenocarcinoma by a bronchoscopic examination, and the patient underwent right lower lobectomy and mediastinal dissection. A histopathological examination revealed IMA extensively invading the right lower lobe and SCC encapsulated within the IMA. The patient was diagnosed with primary pulmonary collision cancer comprising IMA and SCC. Conclusion. The preoperative diagnosis of collision cancer of the lung is difficult; therefore, a detailed pathological examination of the resected specimen is important for achieving an accurate pathological diagnosis and considering adjuvant treatment. Although such cases are very rare, it is important not to overlook simultaneous multiple lung cancers, especially those with extensive IMA.
key words: Lung cancer, Collision cancer, Multiple cancers

Received: March 17, 2021
Accepted: May 28, 2021

JJLC 61 (5): 417-422, 2021