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第40巻第3号目次 | Japanese/English |
 | Full Text of PDF (161K) Article in Japanese |
─ 症例 ─
A Case of Irinotecan-Induced Pneumonitis
Ken-ichiro Inoue, Noriya Hiraoka, Yoshihiro Kasamatsu, Yutaka Kawahito, Keiji Yoshioka, and Sadayoshi YokooFirst Department of Internal Medicine, Matsushita Memorial Hospital, Osaka, Japan.
We report a case of pneumonitis caused by irinotecan (CPT-11). A 55-year-old man was admitted for further evaluation and treatment of small cell lung cancer (SCLC). After irradiation for a focal brain metastatic lesion, irinotecan was administered intravenously. Three weeks after the chemotherapy, he had a high fever with diffuse patchy attenuation on a chest computed tomography (CT) scan. A significant increase in the number of mast cells in his bronchoalveolar lavage (BAL) fluid was also found. The pneumonitis was subsequently controlled by steroid therapy, with a decrease in the number of mast cells in the BAL fluid.
索引用語：Irinotecan, Small cell lung cancer, Pneumonitis, Bronchoalveolar lavage, Mast cell
受付日：1999年11月29日
受理日：2000年3月8日
肺癌 40 (3)：219─221，2000
