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第42巻第3号目次 | Japanese/English |
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─ 原著 ─
Survival of Resected Non-small Cell Lung Cancer Patients According to Pathological Stage
Hidehito Matsuoka1, Wataru Nishio1, Toshihiko Sakamoto1, Hiroaki Harada1, Noriaki Tsubota11Department of Thoracic Surgery, Hyogo Medical Center for Adults, Japan
Objectives. To survey resected non-small cell lung cancer patients who died of cancer and estimate the progression rate of death at each stage in order to determine what stages are particularly associated with micrometastasis. Methods. Of the 815 patients who underwent surgery for primary lung cancer between January 1986 and December 1995, 699 patients without preoperative chemo/radiotherapy were registered. Among these patients, those who died of cancer after at least five years of follow-up were reviewed regarding complete/incomplete resection and pathological stage. Results. A total of 198 patients who underwent complete resection by lobectomy or pneumonectomy died of cancer. The median survival times of these patients were 34.8, 31.5, 33.7, 21.5, 23.5, 20.4 months for stages IA, IB, IIA, IIB, IIIA, IIIB, respectively. There were no significant differences between stages IA and IB (P=0.1088), IB and IIA (P=0.3393), IIB and IIIB (P=0.4907), IIIA and IIIB (P=0.5880). Patients in Group A (stages IA, IB, IIA) died significantly later than those in Group B (stages IIB, IIIA, IIIB) [P<0.0001] . Of 119 incompletely resected patients, 103 died of cancer (Group C). The median survival time of Group C patients was 16.7 months. The difference between Group B and C was not significant (P=0.2100). Conclusion. Two patterns were recognized among the patients. Although patients in Group A and B had different 5-year survivals, patients receiving complete resection and who died of cancer, had a similar curve that of patients who had undergone incomplete resection.
索引用語：Non-small cell carcinoma, Lung cancer, Isolated tumor cell, Micrometastasis
受付日：2001年12月27日
受理日：2002年3月28日
肺癌 42 (3)：181─186，2002
