The Journal of the Japanese Respiratory Society ONLINE JOURNAL

ABSTRACT

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Article in Japanese

Case Report

Pulmonary Pseudallescheriasis in a Patient with Diabetes Mellitus and Alcoholic Liver Cirrhosis

Yoshinobu Saito1) , Masashi Mikami1) , Seiichi Nakamura1) , Noriko Hashimoto1) , Yasuo Abe1) , Michiko Baba1) , Jun Takizawa1) , Masahiko Kawakami1) and Katsuhiko Kamei2)

1)Department of Pneumology, Tokyo Metropolitan Hiroo General Hospital, 2-34-10 Ebisu, Shibuya-ku, Tokyo, 150-0013, Japan 2)Research Center for Pathologic Fungi and Microbial Toxicoses, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba City, Chiba, 260-8673, Japan

ABSTRACT

A 62-year-old man with diabetes mellitus and alcoholic liver cirrhosis was admitted to the hospital because of hemoptysis. Chest X-ray films and computed tomograms showed a dense infiltrative lesion and a healed tuberculous cavity with a possible fungus ball in the upper lobe of the right lung. Bronchoscopy revealed that the hemoptysis originated from the right upper-lobe bronchus. The bleeding stopped after thrombin was applied into the bronchus. Filamentous fungi were seen in lavage fluid from the right upper-lobe bronchus. The fungi were indentified as Pseudallescheria boydii, and pulmonary pseudallescheriasis was diagnosed. The patient was treated successfully with miconazole (400 mg/day) for 2 months. Pseudallescheriasis should be taken into account in the differential diagnosis of aspergilloma-like lesions.

KEYWORDS: Pulmonary pseudallescheriasis, Hemoptysis, Diabetes mellitus, Alcoholic liver cirrhosis, Miconazole

RECEIVED: 1997.11.6

JJRS, 36(5): 498-502, 1998