The Journal of the Japanese Respiratory Society ONLINE JOURNAL
ABSTRACT
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Article in Japanese
Case Report
A case of acute interstitial pneumonia successfully treated with polymyxin B-immobilized fiber column direct hemoperfusion
Masahiro Shimada, Shinobu Akagawa, Masahiro Kawashima, Kimihiko Masuda, Atsuhisa Tamura and Akira Hebisawa
National Hospital Organization (NHO) Tokyo National Hospital
ABSTRACT
A 65-year-old man was admitted because of rapidly progressing respiratory failure with diffuse ground glass opacities according to chest radiography. Acute interstitial pneumonia (AIP) was diagnosed because of diffuse alveolar damage shown by a transbronchial lungs biopsy and the exclusion of any underlying diseases such as infectious diseases. Because steroid pulse therapy did not improve his condition, he was then treated with polymyxin B-immobilized fiber column direct hemoperfusion (PMX-DHP), with excellent results. PMX-DHP should be considered as one of the treatment options for suspected AIP when steroid pulse therapy is ineffective.
KEYWORDS: Polymyxin B-immobilized fiber column direct hemoperfusion: PMX-DHP, Acute interstitial pneumonia: AIP, Diffuse alveolar damage: DAD, Acute respiratory distress syndrome: ARDS
RECEIVED: 2009.5.14
JJRS, 47(12): 1141-1146, 2009