The Journal of the Japanese Respiratory Society ONLINE JOURNAL
ABSTRACT
Full Text of PDF (808k)
Article in Japanese
Case Report
An autopsied case of primary malignant pericardial mesothelioma diagnosed antemortally
Motohiro Kodama1), Hiroki Tateno1), Sadatomo Tasaka1), Kenzo Soejima1), Koichiro Asano1) and Yuichiro Hayashi2)
1)Division of Pulmonary Medicine, Department of Medicine, Keio University School of Medicine
2)Department of Pathology, Keio University School of Medicine
ABSTRACT
A 40-year-old man was admitted to our hospital with a 1-month history of dyspnea and appetite loss. Chest computed tomography and echocardiography showed moderate pericardial effusion and pericardial thickening. The patient had no history of exposure to asbestos. We created a pericardial window in order to make a diagnosis and to relieve the symptoms using video-assisted thoracoscopic surgery and performed biopsies of the pericardium and the pleura. Immunohistologic analysis of the pericardium confirmed a diagnosis of biphasic pericardial mesothelioma. We gave the patient two cycles of chemotherapy, including pemetrexed and platinum, but his condition did not improve and he died 3 months after onset.
KEYWORDS: Malignant pericardial mesothelioma, Pemetrexed, Pericardial window placement
RECEIVED: 2011.5.2
JJRS, 49(12): 964-969, 2011
