The Journal of the Japanese Respiratory Society ONLINE JOURNAL

ABSTRACT

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Article in Japanese

Case Report

A case of bronchocentric granulomatosis resembling lung cancer on diagnostic imaging

Kazuyuki Mimura1), Yoshirou Mochizuki1), Yasuharu Nakahara1), Tetsuji Kawamura1), Rokurou Mimura2) and Youichirou Kobashi3)

1)Department of Respiratory Medicine, National Hospital Organization Himeji Medical Center
2)Department of Pathology, National Hospital Organization Himeji Medical Center
3)Department of Pathology, Tenri Yorozu Hospital

ABSTRACT

A 51-year-old man visited a local physician because of a chest radiographic abnormality which had been pointed out in October 2009 and March 2010. His chest CT images revealed a nodular lesion in the right middle lobe. Since the nodular lesion showed abnormal FDG accumulation on FDG-PET, the physician suspected lung cancer, but was unable to make a definitive diagnosis by CT-guided lung biopsy. The patient was thus referred to our hospital for detailed investigations. A nodular lesion with spiculation and pleural indentation was recognized in the S4 region on chest CT scans which was strongly suspected to be lung cancer. Since various examinations did not provide a definitive diagnosis, we performed surgery. The histological findings of the extirpated tumor were considered to be bronchocentric granulomatosis (BCG), because necrotic granulomatous lesions with epithelioid cells centered on the bronchioles and there was no evidence of fungus or acid-fast bacterium infection.

KEYWORDS: Bronchocentric granulomatosis, Lung cancer, Surgical resection

RECEIVED: 2011.5.18

JJRS, 49(12): 970-975, 2011