The Journal of the Japanese Respiratory Society ONLINE JOURNAL
ABSTRACT
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Article in Japanese
Case Report
A Case of Diffuse Malignant Mesothelioma of the Pleura with Bilateral Chylothorax
Naohiro Shimizudani, Takahisa Morisako, Yoshiko Miyao, Masayuki Ito, Eiichi Hatao, Kiwamu Kiyoi, Akihiko Sudo, Katsuyuki Kobayashi, Fumihiro Tsuchida, Hideki Adachi, Koji Kishi, Hisanaga Yagyu, Syuji Oishi, Hiroyuki Nakamura and Takeshi Matsuoka
The Fifth Department of Internal Medicine, Tokyo Medical University
ABSTRACT
We describe a case of bilateral chylothorax with malignant pleural mesothelioma. A 41-year-old woman was admitted to our hospital because of dyspnea. She had no history of exposure to asbestos. A chest radiograph and chest computed tomogram (CT) on admission revealed massive bilateral pleural effusion and a large tumor with pleural thickening in the left lateral and anterior parts of the pleura and mediastinum. Biochemical tests of pleural fluid revealed chyle. Two years before, she had been diagnosed through histological and histochemical examinations as having diffuse malignant pleural mesothelioma of the epithelial type. Chest-tube drainage was peformed, and pleurodesis was induced by the intrathoracic injection of OK-432 at 10 KE per dose. The chylothorax disappeared after pleurodesis. To date, reports of malignant mesothelioma with nontraumatic chylothorax have been rare.
KEYWORDS: Chylothorax, Mesothelioma, Pleurodesis
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JJRS, 40(10): 832-836, 2002