![](img/midashi_sankaku.gif) |
The Journal of the Japanese Society for Clinical Microbiology |
Biblioraphy Information
ArticleTitle |
Case of late-onset group B streptococcal meningitis in which the transmission route was estimated from an enrichment culture |
Language |
J |
AuthorList |
Nobuyuki Kobayashi1), Minoru Sakurada2), Yoshiyuki Sakai3), Kousuke Tsuchida3), Mitsuyo Kawaguchiya4), Nobumichi Kobayashi4) |
Affiliation |
1) Department of Clinical Laboratory, Hakodate Municipal Hospital
2) Department of Pharmacy, Hakodate Municipal Hospital
3) Department of Pediatrics, Hakodate Municipal Hospital
4) Department of Hygiene, Sapporo Medical University |
Publication |
J.J.C.M.: 31 (2), 82-86, 2021 |
Received |
February 5, 2020 |
Accepted |
November 9, 2020 |
Abstract |
Group B Streptococcus (GBS) is a pathogenic bacterium that causes meningitis in newborns. Obstetrics and gynecological clinical practice guidelines recommend maternal colonization tests cultured on selective media to prevent vertical transmission, but these tests are not sufficiently widespread due to problems such as cost. Here, we present a case in which we took a vaginal culture from the mother of a baby infected with late-onset GBS. We identified GBS only via the selective medium, thus allowing us to determine the infection route. The patient was a 32-day-old infant admitted to the hospital for a fever and lack of vigor. Upon confirming GBS based on pleocytosis in the cerebrospinal fluid as well as cerebrospinal fluid and blood cultures, the patient was diagnosed as having GBS meningitis. However, because the vaginal culture taken from the mother during the 36th week of pregnancy was negative, we performed additional bacterial cultures from another vaginal swab and from her breast milk. The vaginal culture yielded a negative result on the sheep blood agar, and GBS was isolated only from the selective medium. Both breast-milk cultures were negative. The GBS strain detected from the mother was the same as that of the isolate from her infant, suggesting horizontal transmission from the mother. Thus, selective media are useful for GBS carriage testing during pregnancy. |
Keywords |
Streptococcus agalactiae |
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