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The Journal of the Japanese Society for Clinical Microbiology |
Biblioraphy Information
ArticleTitle |
A case of disseminated histoplasmosis complicated with AIDS |
Language |
J |
AuthorList |
Yuzuru Adachi1), Shin Nihonyanagi1,2), Tatsuhiko Wada2), Haruka Kaneki1), Kyoko Kasai1), Tomoyo Onuki1), Nobuhiko Nakazaki1), Keizo Sakurai1), Shinichi Munekata1), Yoko Takayama2), Hikaru Kume3), Katsuhiko Kamei4), Yusaku Kanoh1, 5) |
Affiliation |
1) Department of Medical Laboratory, Kitasato University Hospital
2) Department of Infection Control and Prevention, Kitasato University Hospital
3) Pathology, Kitasato University School of Medicine
4) Medical Mycology Research Center, Chiba University
5) Department of Medical Laboratory, Kitasato University School of Medicine |
Publication |
J.J.C.M.: 31 (2), 87-91, 2021 |
Received |
September 7, 2020 |
Accepted |
November 19, 2020 |
Abstract |
We report our experience of disseminated histoplasmosis, in which Histoplasma capsulatum was detected in all clinical specimens from an HIV-positive patient, including his blood. The patient, a 48-year-old male from Thailand, was considered difficult to treat in another hospital because of a widespread rash and shivering. Therefore, he was transferred to Kitasato University Hospital. A blood culture became positive after four days of cultivation, and yeast-like fungi were detected by Gram staining. However, no fungal growth was observed, even after 48 hours. The Gram stain of the blood culture was repeated and true hyphae, with a septum, were observed. We considered imported mycosis because of the patient's background and identification of the fungal species was requested of the Medical Mycology Research Center, Chiba University. The fungus was identified as H. capsulatum var. capsulatum. In the future, as the number of international travelers increases in Japan, it will become more common to encounter cases with imported mycosis. It is important for clinicians and clinical laboratory technologists to share patient information. |
Keywords |
Histoplasma capsulatum |
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