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The Journal of the Japanese Society for Clinical Microbiology |
Biblioraphy Information
| ArticleTitle |
A case of hyperammonemia and consciousness disturbance due to obstructive urinary tract infection caused by Corynebacterium riegelii |
| Language |
J |
| AuthorList |
Mayo Katsuki1), Kenta Yamaguchi1), Shun Taguchi1), Yukari Sano1), Takayuki Hirano1), Michio Yasunami1), Mami Fukuoka2) |
| Affiliation |
1) Department of Clinical Laboratory, Saga-Ken Medical Centre Koseikan
2) Department of Infection Disease Prevention and Control, Saga-Ken Medical Centre Koseikan |
| Publication |
J.J.C.M.: 32 (4), 257-261, 2022 |
| Received |
February 9, 2022 |
| Accepted |
May 24, 2022 |
| Abstract |
A 80-year-old woman presented to another hospital complaining of epigastric discomfort. She was diagnosed with bilateral hydronephrosis by ultrasonography and referred to our hospital for further evaluation. One week later she decreased in appetite, and then she was transported to our hospital by ambulance with consciousness disturbance. Blood tests showed hyperammonemia but no evidence of hepatic dysfunction. He was diagnosed as urinary tract infection and antimicrobial therapy was started. Bacterial culture of a urine sample collected at hospital admission grew urease-producing Corynebacterium riegelii. The consciousness disturbance failed to improve despite the antibiotic treatment. Since a repeated computed tomography showed worsening of the bilateral hydronephrosis, bilateral ureteral stents were placed. Subsequently, the patient's consciousness disturbance began to improve, along with decreasing circulating ammonia levels. In patients with hyperammonemia causd by non-liver disease, urinary tract infection caused by urease-producing bacteria should be considered. In addition to antimicrobial therapy, unblocking of any urinary tract obstruction is important to improve the symptoms. |
| Keywords |
Corynebacterium riegelii |
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