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The Journal of the Japanese Society for Clinical Microbiology |
Biblioraphy Information
| ArticleTitle |
Helicobacter species infecting humans |
| Language |
J |
| AuthorList |
Emiko Rimbara |
| Affiliation |
Bacteriology II, National Institute of Infectious Diseases |
| Publication |
J.J.C.M.: 33 (1), 1-11, 2022 |
| Received |
August 17, 2022 |
| Accepted |
|
| Abstract |
Helicobacter species are gram-negative helical rods that infect the gastrointestinal tract and liver of humans, birds, and various animals, such as dogs, cats, pigs, and rodents. Helicobacter species are classified into gastric or enterohepatic species, depending on the site of infection. The main Helicobacter species that infect the human stomach is Helicobacter pylori, which is a widely known causative agent of gastric cancer and peptic ulcer. Helicobacter suis, which infects the stomachs of pigs and monkeys, and Helicobacter heilmannii, which infects the stomachs of dogs and cats, are also known to infect the human stomach and cause gastric diseases similar to those by H. pylori. Helicobacter cinaedi is the most frequent enterohepatic Helicobacter species isolated from humans that causes bacteremia and cellulitis in immunocompromised patients. Other enterohepatic species associated with bacteremia include Helicobacter fennelliae, Helicobacter canis, and Helicobacter trogontum. A review of the natural hosts, culture and diagnostic methods, pathogenesis, drug susceptibility, and virulence factors of Helicobacter species is presented with a focus on those species other than H. pylori that infect humans. |
| Keywords |
Helicobacter pylori, Helicobacter cinaedi, Helicobacter suis, Helicobacter heilmannii |
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