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The Journal of the Japanese Society for Clinical Microbiology |
Biblioraphy Information
| ArticleTitle |
Prediction of antimicrobial resistance by follow-up urinary gram-stain for pyelonephritis |
| Language |
J |
| AuthorList |
Masafumi Abe1), Satoshi Yoshikawa1), Kazusa Saegusa2), Takeshi Ueda1) |
| Affiliation |
1) Department of Emergency and General Internal Medicine, Rakuwakai Marutamachi Hospital
2) Department of Allergy and Rheumatology, Graduate School of Medicine, The University of Tokyo |
| Publication |
J.J.C.M.: 33 (1), 69-71, 2022 |
| Received |
January 12, 2022 |
| Accepted |
May 13, 2022 |
| Abstract |
The effectiveness of antibiotic therapy for the treatment of pyelonephritis is typically evaluated by the clinical course and results of urine culture. The purpose of this study was to evaluate the usefulness of follow-up urinary gram-stain. We analyzed the results of hospitalized pyelonephritis patients treated in our department. We investigated whether follow-up urinary gram-stain within 48 hours after initiating antibiotic treatment can help predict resistance to antibiotics at an early stage. 271 patients were enrolled in the study. The diagnostic accuracy of using follow-up gram-stain to predict the presence of antibiotic-resistant bacteria was as follows: sensitivity: 41%, specificity: 82%, positive likelihood ratio: 2.32, and negative likelihood ratio: 0.71. In particular, elongated cells may lead to early prediction of resistant bacteria, and further studies are needed. |
| Keywords |
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