 |
The Journal of the Japanese Society for Clinical Microbiology |
Biblioraphy Information
ArticleTitle |
Laboratory Diagnostic Methods for Clostridioides difficile |
Language |
J |
AuthorList |
Hiroyuki Kunishima |
Affiliation |
Department of Infectious Diseases, St. mariannna University School of Medicine |
Publication |
J.J.C.M.: 33 (3), 175-179, 2023 |
Received |
March 29, 2023 |
Accepted |
|
Abstract |
Clostridioides difficile is the most common anaerobic bacterium in healthcare facilities and is widely isolated from humans, animals, and the environment. C. difficile can cause nosocomial infections because it forms spores and is alcohol-resistant. Because of its high sensitivity, the NAAT test has been reported to shorten the time required to administer CDI drugs, reduce the need for additional tests, and shorten hospital stays, thereby reducing healthcare costs. Due to the Covid-19 pandemic, various rapid molecular identification systems have been introduced in many medical facilities, and NAAT testing can be performed from the beginning, including small and medium-sized hospitals. Medical facilities need to carefully examine and diagnose the disease in collaboration with infectious disease physicians, laboratory specialists, and certified clinical microbiologists, taking into consideration the characteristics of rapid diagnostic tests using GDH and toxin, NAAT tests, and culture tests. |
Keywords |
Clostridioides difficile, GDH, NAAT |
|