Journal

The Journal of the Japanese Society for Clinical Microbiology

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[Vol.33 No.4 contents]
Japanese / English

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Article in Japanese

ArticleTitle A case of Infective endocarditis due to Lacticaseibacillus paracasei successfully managed with appropriate usage of antibacterial agents guided by Blood culture Gram stain
Language J
AuthorList Yohei Sonoya1,4,6), Osamu Fukuda2), Yusuke Ota3), Ryoichi Saito3), Yoshiyuki Sumita1), Yukihiro Kaneko4,5), Makoto Sata6)
Affiliation 1) Department of Clinical Laboratory, National Research and Development Agency National Cerebral and Cadiovascular Center
2) Department of Clinical Laboratory, National Hospital Organization Osaka National Hospital
3) Department of Molecular Microbiology, Graduate School of Medicine and Dental Science, Tokyo Medical and Dental University
4) Department of Bacteriology, Osaka Metropolitan University, Graduate School of Medicine
5) Research Center for Infectious Disease Sciences, Osaka Metropolitan University, Graduate School of Medicine
6) Department of Infection Control and Prevention, National Research and Development Agency National Cerebral and Cadiovascular Center
Publication J.J.C.M.: 33 (4), 275-279, 2023
Received April 20, 2023
Accepted May 31, 2023
Abstract In this study, we report a case of infective endocarditis caused by Lacticaseibacillus paracasei, which was diagnosed based on Gram stain findings at the time of positive blood culture, which suggested the genus Lactobacillus, which is known to be intrinsically resistant to vancomycin, and allowed early therapeutic intervention based on effective antimicrobial selection. The patient was a woman in her 80s. All two sets of blood cultures taken on admission were positive, and Gram stain showed Gram-positive bacilli with no spores, large size, linear shape, and chain formation. Blood cultures taken after antimicrobial therapy were negative. No complications of embolism were observed due to early initiation of effective antimicrobial agents. The treatment of severe infections, including those with positive blood cultures, is a race against time, and it is important to actively inform the clinician about the Gram stain findings.
Keywords Lacticaseibacillus paracasei
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