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The Journal of the Japanese Society for Clinical Microbiology |
Biblioraphy Information
| ArticleTitle |
First case of Christensenella hongkongensis bacteremia in Japan |
| Language |
J |
| AuthorList |
Haruka Yokoo1), Naoya Ogura1), Ayako Nakamura1), Masami Sugihara1), Kento Goto2), Shiori Sasahara3), Daisuke Sugimoto3), Hidenori Yoshii3) |
| Affiliation |
1) Department of Clinical Laboratory, Juntendo Tokyo Koto Geriatric Medical Center
2) Department of General Medicine, Juntendo Tokyo Koto Geriatric Medical Center
3) Department of Medicine, Diabetology and Endocrinology, Juntendo Tokyo Koto Geriatric Medical Center |
| Publication |
J.J.C.M.: 33 (4), 280-284, 2023 |
| Received |
March 22, 2023 |
| Accepted |
June 2, 2023 |
| Abstract |
We experienced a case of bacteremia caused by Christensenella hongkongensis. The patient, a man in his 70s with type 2 diabetes admitted to our hospital for the purpose of education of diabetes. He developed a fever in the 37°C range on the 12th day, elevated C-reactive protein (CRP) levels and mild pneumonia were observed on the 14th day. He was discharged on the 29th day after administration on ampicillin/sulbactam. Blood culture was positive at 77 hours, and showed a gram-positive short bacilli. The isolate grew as micro colonies of anaerobic incubation at 35°C, and was not identified by phenotypic identification methods using the Rap ID ANA, and identified as C. hongkongensis by 16S rRNA sequencing. Initially we reported as a possible Eggerthella species based on morphology and the results of antimicrobial susceptibility testing. However, due to the slow growth, we suspected another species and scrutinized. It is difficult to distinguish clearly from Eggerthella and related species, and 16S rRNA sequencing is necessary to confirm C. hongkongensis. Gastrointestinal lesions are considered to be an important finding in presuming the presence of C. hongkongensis because this bacterium is endemic in the gastrointestinal tract. This case is the first published in a paper of C. hongkongensis bacteremia in Japan. |
| Keywords |
Christensenella hongkongensis, Anaerobe, gram positive rod, bacteremia, diabetes mellitus |
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