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The Journal of the Japanese Society for Clinical Microbiology |
Biblioraphy Information
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[Vol.34 No.1 contents] Japanese / English |
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| ArticleTitle | A case of multifocal brain abscess caused by Rothia dentocariosa prothetic valve endocarditis |
| Language | J |
| AuthorList | Shun Taguchi1), Kenta Yamaguchi1), Akari Izumi1), Tomohiko Yano1), Mayo Katsuki1), Yukari Sano1), Atsumi Yokoo2), Yumiko Funashima3), Zenzo Nagasawa3), Takayuki Hirano1), Michio Yasunami1), Yuki Nishimura4), Mami Fukuoka5) |
| Affiliation |
1) Department of Clinical Laboratory, Saga-Ken Medical Centre Koseikan 2) Department of Clinical Laboratory, Takagi Hospital 3) Department of Medical Technology and Sciences School of Health Sciences at Fukuoka International University of Health and Welfare 4) Department of Cardiology, Saga-Ken Medical Centre Koseikan 5) Department of Infection Control, Saga-Ken Medical Centre Koseikan |
| Publication | J.J.C.M.: 34 (1), 42-48, 2023 |
| Received | July 18, 2023 |
| Accepted | October 18, 2023 |
| Abstract | An eighty-nine old woman who was under the treatment of dental caries for one year, was taken to the emergency room of our hospital because of an episode of high fever over 40°C after long lasting slight fever for one month. She had been followed up at our hospital after the aortic valve replacement surgery for four years at the time. She received intravenous cefmetazole after taking two sets of blood culture samples, under the tentative diagnosis of sepsis/urinary tract infection. Two days later, the two aerobic blood cultures turned to be positive for Gram-positive bacilli, and the bacteria was identified as Rothia dentocariosa by mass-spectrometry using VITEK MS. Although there was no overt vegetation on the cardiac echograms, the petechiae in the right conjunctiva and the multiple small foci of cerebral infarction suggested the presence of infective endocarditis (IE) according to Duke's diagnostic criteria. The antibiotic treatment was de-escalated to Penicillin G (PCG) and was continued for six weeks according to the standard treatment of prothetic valve endocarditis. Then three-week treatment with PCG was added because of multifocal brain abscess found by following-up MRI. The patient was discharged from the hospital after the confirmation of improvement of the brain abscess by MRI. The detection of R. dentocariosa in blood culture is rare, but it indicates the oral and cardiovascular evaluations. |
| Keywords | Rothia dentocariosa |
| Copyright © 2002 The Japanese Society for Clinical Microbiology All rights reserved. |