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The Journal of the Japanese Society for Clinical Microbiology |
Biblioraphy Information
ArticleTitle |
Assessment of DPS192iX for susceptibility testing on both Streptococcus spp. and H. influenzae |
Language |
J |
AuthorList |
Keisuke Nishikawa1), Kenichiro Ohnuma1,2), Mari Kusuki1,2), Nami Ishida1), Saori Kobayashi1), Masako Nishida1), Sayaka Matsumoto1), Natsuki Yoshida1), Ryohei Umemoto1), Goh Ohji1,2,3), Takayuki Miyara2), Takamitsu Imanishi1), Yoshihiko Yano1,4) |
Affiliation |
1) Department of Clinical Laboratory, Kobe University Hospital
2) Department of Infection Prevention and Control, Kobe University Hospital
3) Division of Infectious Diseases Therapeutics, Department of Microbiology and Infectious Diseases, Kobe University Graduate School of Medicine
4) Division of Gastroenterology, Department of Internal Medicine, Kobe University Graduate School of Medicine |
Publication |
J.J.C.M.: 35 (2), 138-143, 2025 |
Received |
October 24, 2024 |
Accepted |
January 17, 2025 |
Abstract |
We evaluated the performance of DPS192iX (Eiken Chemical Co., Ltd.), which determines MICs hourly, on both Streptococcus spp. and Haemophilus influenzae. Sixty-eight Streptococcus spp. and seventy-eight H. influenzae isolates were used in this study. The concordances (within+/−1 difference in each tube) were ≥ 97% and ≥ 90% (except imipenem) on Streptococcus spp. and H. influenzae, respectively. Conversely, very major errors were observed in some drugs, including A/C and S/A on H. influenzae. Moreover, we noted that the resistances to levofloxacin and macrolides of Streptococcus spp. were confirmed at 5 and 6 h of incubation, respectively. In H. influenzae, the resistance to ampicillin of BLPAR and BLNAR/BLPACR strains was detected at 8 and 9 h of incubation, respectively. The results of this study suggest that susceptibility testing using DPS192iX might contribute to the rapid detection of resistant bacteria. |
Keywords |
Haemophilus influenzae, DPS192iX, BLNAR |
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