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The Journal of the Japanese Society for Clinical Microbiology |
Biblioraphy Information
| ArticleTitle |
A case of pyogenic knee arthritis caused by Neisseria meningitidis after returning from abroad |
| Language |
J |
| AuthorList |
Saori Muto1), Airi Kobayashi1), Yujiro Shimizu1), Chinami Toyoda1), Yuuko Yamauchi2), Tsukasa Ariyoshi3) |
| Affiliation |
1) Department of Clinical Laboratory, Tokyo Metropolitan Hiroo Hospital
2) Department of Infection Disease, Tokyo Metropolitan Hiroo Hospital
3) Department of Microbiology, Tokyo Metropolitan Institute of Public Health |
| Publication |
J.J.C.M.: 35 (3), 237-242, 2025 |
| Received |
February 5, 2025 |
| Accepted |
May 20, 2025 |
| Abstract |
Neisseria meningitidis is a gram-negative diplococcus that can infect the cerebrospinal fluid, blood, or other sterile sites. In Japan, doctors are required to report cases of invasive meningococcal disease as category five infectious diseases to the Ministry of Health, Labour and Welfare. Here, we report a case of pyogenic knee arthritis caused by N. meningitidis in a 30s woman returning from Uzbekistan. Four days after returning to Japan, she presented to our hospital with fever and right knee pain. Gram-negative diplococci were detected in the knee joint fluid and synovial membrane. Biochemical characterization was rapidly performed using the ID test HN-20 rapid and, which confirmed the identity of the bacterium as N. meningitidis with a probability of 92. Moreover, identification using MALDI Biotyper confirmed the species identity as N. meningitidis. Analysis by the National Institute of Infectious Diseases showed that the capsular polysaccharide serogroup was W and the genotype was ST-11. This case of pyogenic knee arthritis caused by N. meningitidis was likely an imported case from overseas. |
| Keywords |
Neisseria meningitidis |
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