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The Journal of the Japanese Society for Clinical Microbiology |
Biblioraphy Information
ArticleTitle |
Evaluation of Isolation of Mycobacterium kansasii Based on hsp65-Typing: A Report from a Clinical Laboratory in a Japanese University Hospital |
Language |
J |
AuthorList |
Ayumi Hiishi1), Setsuko Tazawa4), Yuji Arai1), Kazuhisa Ugajin5), Akiko Anan1), Mayumi Togashi1), Hisako Nakamura1), Naoyuki Yazawa1), Yutaka Tsuchiya2), Munetaka Hayashi3), Kenji Marumo4) |
Affiliation |
1) Division of Clinical Laboratory, 2) Department of Respiratory Medicine,
3) Department of Emergency Center,
4) Department of Clinical Pathology in Showa University Fujigaoka Hospital, and
5) Division of Clinical Laboratory in Showa University |
Publication |
J.J.C.M.: 22 (1), 49-53, 2012 |
Received |
September 21, 2011 |
Accepted |
January 13, 2012 |
Abstract |
The isolation of Mycobacterium kansasii in a Japanese university hospital has not been evaluated in detail. We retrospectively investigated the isolation background of 10 M. kansasii strains determined by hsp65-typing in Showa University Fujigaoka Hospital in Japan during the eight years between 2003 and 2010. Of eight cases with type I, four were treated for pulmonary infection. Of the two cases without type I, one was a new type II containing one silent mutation (GenBank: accession no. JF836805), compared with sequences that have been reported until now, and another was type III, consistent with the known sequence (GenBank: accession no. AY438087). M. kansasii containing types I and II associated with pathogenicity showed high-catalase production with a semi-quantitative catalase test. Although the number of cases in this study was small, hsp65-typing possibly play an important role as a supportable test for evaluating the cause of M. kansasii infection. |
Keywords |
Mycobacterium kansasii |
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