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The Journal of the Japanese Society for Clinical Microbiology |
Biblioraphy Information
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[Vol.22 No.1 contents] Japanese / English |
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| ArticleTitle | A Case of Vancomycin Low-Level Susceptibility Staphylococcus capitis subsp. ureolyticus Isolated from Blood Culture |
| Language | J |
| AuthorList | Takako Iwamoto1,2), Yukari Sumi1), Mika Shinnai1,2), Kazuhiro Matuo2), Takiko Kanzaki2), Masamichi Amasaki2), Naomi Kunichika2), Noriko Ohbuchi2), Ryo Kadoya2), Yukie Terayama3), Kyoko Sikichi4), Hidekazu Mizuno4), Kumiko Kai5), Kunikazu Yamane5), Yoshichika Arakawa5) |
| Affiliation |
1) Department of Clinical Laboratory, Yamaguchi Red Cross Hospital 2) Infection Control Team, Yamaguchi Red Cross Hospital 3) Department of Clinical Laboratory, Ogori Daiichi General Hospital 4) Department of Clinical Laboratory, Yamaguchi University Hospital 5) Department of Bacterial Pathogenic and Infection Control, National Institute of Infection Diseases |
| Publication | J.J.C.M.: 22 (1), 54-59, 2012 |
| Received | November 1, 2010 |
| Accepted | December 5, 2011 |
| Abstract | This report describes a case of isolated low-level resistance to vancomycin (VCM) with Staphylococcus capitis subsp. ureolyticus (S. capitis-ureo) confirmed by blood culture and central venous catheter (CVC) tip culture from the patient indwelling CVC. Antimicrobial susceptibility testing by different instrumental method gave the same results, the minimum inhibitory concentration (MIC) of VCM was 8-16 μg/ml, for the isolation by blood culture. PCR assay results for detection of vanA, vanB, vanC1 and vanC2/C3 gene were all negative. We assumed this case might have developed low-level resistance to glycopeptide during prolonged exposure to the agents. Although this case was cured by catheter removal, it is necessary to pay attention to the detection low-level resistance to vancomycin with S. capitis-ureo and researching for antimicrobial susceptibility test. |
| Keywords | Staphylococcus capitis subsp. ureolyticus, teicoplanin |
| Copyright © 2002 The Japanese Society for Clinical Microbiology All rights reserved. |