 |
The Journal of the Japanese Society for Clinical Microbiology |
Biblioraphy Information
| ArticleTitle |
A case of community-acquired pseudomembranous colitis caused by binary toxin-positive Clostridioides difficile (Clostridium difficile) |
| Language |
J |
| AuthorList |
Saori Ishimura1,2), Tamaki Orita1), Atsuko Kobayashi2), Haru Kato3) |
| Affiliation |
1) Clinical Laboratory, Takarazuka City Hospital
2) Infection Control Office, Takarazuka City Hospital
3) Department of Bacteriology II, National Institute of Infectious Diseases |
| Publication |
J.J.C.M.: 27 (4), 313-319, 2017 |
| Received |
February 20, 2017 |
| Accepted |
June 21, 2017 |
| Abstract |
We report a case of community-acquired pseudomembranous colitis caused by binary toxin-positive Clostridioides difficile (Clostridium difficile). The patient had watery diarrhea and neurological symptoms following dehydration and admitted to hospital. He had no history of hospitalization and use of antibiotics in two months before onset. The test results of enzyme-immunoassay detecting both glutamate dehydrogenase and toxins A/B in stool specimen were negative on the 3rd day of admission. However, endoscopy findings showed typical formation of pseudomembrane in the large intestine. C. difficile recovered from this case was toxin A-positive, toxin B-positive, binary toxin-positive, and identified as PCR-ribotype 019/slpA sequence type cr-03. Further studies are warranted to know the role of binary toxin-positive strains in C. difficile infection including community- acquired infection. |
| Keywords |
glutamate dehydrogenase（GDH）, binary toxin |
|
