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The Journal of the Japanese Society for Clinical Microbiology |
Biblioraphy Information
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[Vol.29 No.3 contents] Japanese / English |
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| ArticleTitle | A case of bacteremia caused by Methylobacterium radiotolerans |
| Language | J |
| AuthorList | Natsumi Suda1), Toshiko Obara1), Kazuki Nakamura1), Masaei Onuma2), Michiko Yoshida3), Hiroaki Baba4), Mitsuo Kaku4), Hiroki Sakurai5) |
| Affiliation |
1) Department of Clinical Laboratory, Miyagi Children's Hospital 2) Division of Hematology and Oncology, Department of Pediatrics, Miyagi Children's Hospital 3) Office for Infection Control, National Center for Child Health and Development 4) Department of Infection Control and Laboratory Diagnostics, Internal Medicine, Tohoku University Graduate School of Medicine 5) Division of Rheumatology and Infectious Disease, Department of Pediatrics, Miyagi Children's Hospital |
| Publication | J.J.C.M.: 29 (3), 152-157, 2019 |
| Received | December 20, 2018 |
| Accepted | March 8, 2019 |
| Abstract | Here we describe a neutropenic patient suffering from bacteremia caused by Methylobacterium radiotolerans which was successfully treated with ciprofloxacin. A 13-year-old girl with a diagnosis of acute myeloid leukemia presented with prolonged fever. After 8 days of incubation, a blood culture grew a Gram-negative bacilli with vacuoles, pink colonies and it was identified as M. radiotolerans. Longer incubation period is required to glow in blood culture bottle for this species. Matrix assisted laser desorption/ionization time of flight mass spectrometry (MALDI-TOF MS) may be useful for rapid identification of this species, because it is difficult to identify only with conventional methods. Methylobacterium species usually shows to be susceptible to new-quinolones and aminoglycosides, but resistant to beta-lactams. Therefore early recognition of this species based on characteristic colony appearance, and Gram's staining are significantly important because beta-lactam antibiotics are exclusively chosen as empiric therapy in cases of neutropenic fever. |
| Keywords | Methylobacterium radiotolerans, MALDI-TOF MS |
| Copyright © 2002 The Japanese Society for Clinical Microbiology All rights reserved. |