Journal

The Journal of the Japanese Society for Clinical Microbiology

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[Vol.30 No.1 contents]
Japanese / English

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Article in Japanese

ArticleTitle A case of infective endocarditis complicated with vertebral osteomyelitis by Granulicatella adiacens
Language J
AuthorList Yukie Katayama1), Nami Izumiya1), Akiko Kura1), Kyouko Hirose1), Susumu Motochi1), Keigo Komai1), Hiroshi Yoneyama2), Sugako Kanayama2)
Affiliation 1) Department of Clinical Laboratory, Asanogawa General Hospital
2) Internal Medicine, Asanogawa General Hospital
Publication J.J.C.M.: 30 (1), 25-29, 2019
Received February 14, 2019
Accepted September 18, 2019
Abstract We wxperience a case of infective endocarditis complicated with vertebral osteomyelitis by Granulicatella adiacens, an one of nutritionally variant streptococci (NVS). The patient, a sixty-year-old man, visited our hospital complaining of lower back pain and poor appetite. During examination he exhibited cardiac murmurs, and his chest X-ray showed cardiac enlargement and pleural effusion. Echocardiography revealed heart failure due to mitral insufficiency and aortic insufficiency. MRI images of the spine showed lumbar (L4, L5) vertebral osteomyelitis and discitis. Gram positive streptococci were detected from blood cultures collected after admission, and were identified as Granulicatella adiacens using matrix-assisted laser desorption/ionization time of flight mass spectrometry (MALDI-TOF MS). An echocardiogram was performed again on the patient and images showed suspected vegetation on the right coronary apex of the aortic valve. After antimicrobial therapy, he underwent mitral and aortic valve replacement surgery. Vegetation attached to the anterior leaflet of the mitral and aortic valve was confirmed. Although vertebral osteomyelitis due to NVS is rare, it needs to be recognized as a complication of infective endocarditis.
Keywords Granulicatella adiacens
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