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The Journal of the Japanese Society for Clinical Microbiology

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[Vol.30 No.3 contents]
Japanese / English

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Article in Japanese

ArticleTitle A case with suspected allergic bronchial pulmonary mycosis by Schizophyllum commune
Language J
AuthorList Mitsuko Fujita1), Rie Uemura1), Hiroyuki Nakamura2), Kiyotaka Tanimoto3), Takuya Inoue4), Kiyoshi Negayama5), Katsuhiko Kamei6)
Affiliation 1) Division of Clinical Laboratory Medicine, Sakaide City Hospital
2) Department of Internal Medicine, Sakaide City Hospital
3) Department of Pediatrics, Sakaide City Hospital
4) Department of Internal Medicine Division of Hematology, Respiratory Medicine Faculty of Medicine, Kagawa University
5) Division of Clinical Laboratory Medicine, Kagawa University Hospital
6) Division of Clinical Research, Medical Mycology Research Center, Chiba University
Publication J.J.C.M.: 30 (3), 149-153, 2020
Received December 25, 2019
Accepted April 14, 2020
Abstract We experienced a case of suspected allergic bronchial pulmonary mycosis (ABPM) by Schizophyllum commune. The male patient was in his 60s, with a history of diabetes mellitus and an enlarged prostate. He was admitted to our hospital because of fever and cough, and a chest radiograph showed an infiltrative shadow in the right upper lung field. Antimicrobial agents were prescribed but his condition did not improve, so he was referred to the Respiratory Medicine department. A mucoid impaction was found by bronchoscopy, and a filamentous fungus was found by gram stain of the mucoid impaction. In the culture, growth of white fluffy colonies was observed, and it was identified as S. commune by mass spectrometry and genetic examination. In serological examination by ELISA, both IgG and IgE antibodies against S. commune were strongly positive. As a result, it was diagnosed that ABPM by S. commune was strongly suspected, and treatment with itraconazole and steroid was performed for 6 months.
Keywords Schizophyllum commune
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