Journal

The Journal of the Japanese Society for Clinical Microbiology

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[Vol.31 No.1 contents]
Japanese / English

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Article in Japanese

ArticleTitle A case of neonatal gonococcal conjunctivitis suggesting the need for appropriate culture tests
Language J
AuthorList Kazuaki Kameyama1), Shogo Otake2), Ken Shimuta3), Hideyuki Takahashi3), Masatomo Morita3), Makoto Ohnishi3), Yui Shimizu1), Tomoko Oue1), Masashi Kasai2)
Affiliation 1) Department of Clinical Laboratory, Hyogo Prefectural Kobe Children's Hospital
2) Department of Infectious diseases, Hyogo Prefectural Kobe Children's Hospital
3) Department of Bacteriology I, National Institute of Infectious Diseases
Publication J.J.C.M.: 31 (1), 22-26, 2020
Received April 23, 2020
Accepted September 14, 2020
Abstract Neisseria gonorrhoeae is one of the causative agents of neonatal conjunctivitis, but its incidence rate is very low in developed countries, including Japan. We report a case of neonatal conjunctivitis caused by N. gonorrhoeae. A 9-day-old male infant was presented to our emergency department with left eye discharge, left eyelid swelling, and fever. We suspected neonatal gonococcal conjunctivitis and performed rapid gram staining of his eye discharge. Because gram-negative diplococci were observed, we prescribed ceftriaxone. His symptoms then improved, and he was discharged without any prognostic symptoms. Eventually, N. gonorrhoeae ST13840 was detected as a result of culture examination and molecular typing by multi-locus sequence typing. Neonatal gonococcal conjunctivitis is a very rare but serious disease that causes blindness without appropriate treatment. We suggest the proper use of ophthalmic antibiotics at birth, need for a screening test in pregnancy to prevent N. gonorrhoeae infection, and need to educate healthcare workers about appropriate specimen storage and culture tests.
Keywords Neisseria gonorrhoeae
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