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The Journal of the Japanese Society for Clinical Microbiology |
Biblioraphy Information
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[Vol.14 No.4 contents] Japanese / English |
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| ArticleTitle | A 12-Year Longitudinal Assessment for Changes in Methicillin-resistant Staphylococcus aureus Strains Isolated in a University Teaching Hospital |
| Language | J |
| AuthorList | Toshi Nada1), Hisashi Baba1,2), Yasuhito Goto1), Sayoko Nishio1), Teruko Ohkura1), Yukiko Nakanishi1), Mariko Mochizuki1), Kaori Suzuki3), Kumiko Kawamura4), Masato Yamamoto5), Yoshitsugu Iinuma6), Satoshi Ichiyama6), Michio Ohta7) |
| Affiliation |
1) Department of Clinical Laboratory Medicine, Nagoya University Hospital 2) Department of Infectious Diseases, Nagoya University Hospital 3) Department of Clinical Laboratory Medicine, Moriyama Municipal Hospital, City of Nagoya 4) Department of Medical Technology, School of Health Sciences, Nagoya University 5) Department of Neuropsychopharmacology and Hospital Pharmacy, Nagoya University Graduate School of Medicine 6) Department of Clinical Laboratory Medicine, Graduate School of Medicine, Kyoto University 7) Department of Molecular Bacteriology, Nagoya University Graduate School of Medicine |
| Publication | J.J.C.M.: 14 (4), 215-222, 2004 |
| Received | June 14, 2004 |
| Accepted | October 6, 2004 |
| Abstract | To evaluate trends in annual number of methicillin-resistant Staphylococcus aureus (MRSA) isolates and antibiotic susceptibility, we analyzed the data concerning the 7,544 strains of MRSA isolated in Nagoya University Hospital from April 1992 through March 2004. The annual number of MRSA isolates showed a tendency to decrease after fiscal 1998, although that increased from fiscal 1992 to fiscal 1998. This decrease of MRSA isolates in recent years was thought as a result of improvement in hospital infection control. It was reported that community-acquired MRSA infections increased recently, however, no significant change was seen in the number and isolation frequency of MRSA obtained from outpatients in this study. Through these 12 years, specimens from respiratory system and pus constituted more than 60% of all specimens that yielded MRSA. There were no vancomycin-resistant strains, whereas one strain was resistant to teicoplanin, and 0.2 to 4.5% of MRSA strains were resistant to arbekacin. The annual sensitivity rates among MRSA isolates to minocycline and fluoroquinolones gradually decreased during this study, whereas the annual rate of sensitivity to gentamicin significantly increased from 36.9% in fiscal 1992 to 62.2% in fiscal 2003. |
| Keywords | MRSA |
| Copyright © 2002 The Japanese Society for Clinical Microbiology All rights reserved. |