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The Journal of the Japanese Society for Clinical Microbiology |
Biblioraphy Information
| ArticleTitle |
The Analysis of MRSA Strains by PFGE and the Infection Control Strategies in NICU |
| Language |
J |
| AuthorList |
Makiko Kiyosuke1), Kazuo Sato2), Masato Seki2), Megumi Takayanagi3), Zenzo Nagasawa3)4), Akira Koguchi4), Ariaki Nagayama4) |
| Affiliation |
1) Department of Clinical Laboratory, Clinical Research Institute, National Hospital Organization Kyushu Medical Center
2) Department of Pediatrics, National Hospital Organization Kyushu Medical Center
3) Department of Laboratory, Saga Medical School Hospital
4) Department of Immunology and Microbiology, School of Medicine, Fukuoka University |
| Publication |
J.J.C.M.: 15 (1), 25-31, 2005 |
| Received |
April 14, 2004 |
| Accepted |
January 24, 2005 |
| Abstract |
In National Kyushu Medical Center, almost half of the new patients carrying MRSA were detected from the babies hospitalized in neonatal intensive care unit (NICU), and MRSA was one of the most important pathogens for nosocomial infection in the NICU. For epidemiologic survey, we analyzed the genotype of 62 MRSA strains isolated between December 1999 and May 2002 in the NICU using pulsed field gel electrophoresis. The examined strains were consequently classified into 11 groups and an epidemic period due to type G, which was the most frequently isolated genotype, was observed in 2000. Furthermore, we attempted to detect MRSA from the environment of NICU and the nasal cavities of NIU staffs. MRSA strains were isolated from the surrounding of the patients and some of the staff's nasal cavities. The genotype analysis of these strains with PFGE revealed that all of them were identified type G. These results suggest that the environment of the patient was contaminated with MRSA when the outbreak due to MRSA was occurred. Therefore, we organized Infection Control Team in NICU and took precautions against nosocominal infections. The isolation rate of MRSA was dramatically decreased after the introduction of the precautions. We believed that the most effective precaution for the prevention of contact infection was the wear of gloves when we care for the patients. |
| Keywords |
MRSA, NICU |
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