Journal

The Journal of the Japanese Society for Clinical Microbiology

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[Vol.15 No.2 contents]
Japanese / English

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Article in Japanese

ArticleTitle Incidence of Vancomycin-resistant Enterococcus (VRE) in Gifu Prefecture: Evalution of the Validity of Fully Automated Microbiology Systems
Language J
AuthorList Kazukiyo Yamaoka1), Ikuyo Iwata2), Kiyoyasu Okuda2), Youko Matukawa3), Haruki Sawamura4), Kazue Ueno5)
Affiliation 1) Gifu College of Medical Technology
2) Clinical Laboratory of Gifu Prefectural Gifu Hospital
3) Clinical Laboratory of Gifu Prefectural Tajimi Hospital
4) Clinical Laboratory of Gifu University General Hospital
5) Professor emeritus of Gifu University
Publication J.J.C.M.: 15 (2), 77-81, 2005
Received December 7, 2004
Accepted April 8, 2005
Abstract Five strains of enterococci with reduced susceptibility to Vancomycin (VCM) were isolated from three hospitals in Gifu Prefecture between January 2003 and July 2004. These five strains were retested in identification and susceptibility with the same fully automated microbiology systems, with PCR detection of VRE genes. Identification of all strains produced the same results, however, susceptibility of four strains showed VCM-susceptible. Only one strain showed VCM-resistance with MIC of 256 μ g/ml or over in gradient diffusion test (E-test), carrying a vanA gene. The patient who had VRE was 52-year-old man with long-term use of VCM for the treatment of MRSA septicemia and MRSA pneumonia. VRE were isolated from stool sample for screening culture. When VRE is detected using fully automated microbiology system, identification and susceptibility shoud be rested before final reporting. Screening culture may be recommended in patients with long-term use of VCM to prevent the spread of VRE in the hospital.
Keywords VRE
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