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The Journal of the Japanese Society for Clinical Microbiology |
Biblioraphy Information
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[Vol.16 No.3 contents] Japanese / English |
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| ArticleTitle | Localized Type of Primary Cutaneous Nocardiosis Caused by Nocardia brasiliensis -A Case Which Shows the Effectiveness of Levofloxacin- |
| Language | J |
| AuthorList | Masanori Ohkuma1), Isamu Ikeda2), Zenzo Nagasawa3), Tomomichi Ono4) |
| Affiliation |
1) Department of Laboratory Medicine, Kumamoto University Hospital (Former Position Department of Laboratory, Social Insurance Ohmuta-Tenryo Hospital) 2) Department of Dermatology, Social Insurance Ohmuta-Tenryo Hospital 3) Department of Laboratory, Saga University Faculty of Medicine 4) Vice President, Kumamoto University |
| Publication | J.J.C.M.: 16 (3), 145-150, 2006 |
| Received | November 1, 2005 |
| Accepted | May 8, 2006 |
| Abstract | We have experienced a case of localized cutaneous nocardiosis caused by Nocardia brasiliensis. The case, 75-year-old-male, injured his knee by an old floorboard and developed a necrotic ulcer with pus and fistulae. Oral cefdinir after ulcer debridement did not show any clinical improvements, so was switched to levofloxacin, then the ulcer healed within two weeks. Diagnosed as localized cutaneous nocardiosis from the isolated N. brasiliensis and the clinical features. Although sulfamethoxazole/trimethoprim is most effective and should be the first-choice drug, other drugs also could be chosen after identification and antibiotic susceptibility test. In this case, levofloxacin proved to be quite effective both in vitro and in vivo. While quinolones would induce drug-resistance of bacteria, our study suggests quinolones also could be chosen for nocardiosis when other drugs can not be chosen. |
| Keywords | cutaneous nocardiosis, Nocardia brasiliensis, levofloxacin |
| Copyright © 2002 The Japanese Society for Clinical Microbiology All rights reserved. |