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The Journal of the Japanese Society for Clinical Microbiology |
Biblioraphy Information
| ArticleTitle |
A Case of Bacillus cereus Sepsis in a Patient with Acute Myeloid Leukemia |
| Language |
J |
| AuthorList |
Kenji Inagaki1), Yoshihiro Inamoto2), Nobuaki Hukusima2), Yoshihito Otsuka3),4), Chie Yanagisawa4), Hideaki Hanaki4), Hidenori Morikawa1), Yohei Fujimoto1), Takafumi Katayama1), Mieko Ishikawa1), Atsuko Kito1), Tatsunao Sugiura2), Keitaro Tsushita2), Shingo Sonoda1) |
| Affiliation |
1) Laboratory of medicine, Social Insurance Chukyo Hospital
2) Department of Hematology, Social Insurance Chukyo Hospital
3) Laboratory of medicine, Social Insurance Central General Hospital
4) Kitasato Research Center for Anti-infection Drugs |
| Publication |
J.J.C.M.: 17 (2), 119-123, 2007 |
| Received |
November 1, 2006 |
| Accepted |
March 28, 2007 |
| Abstract |
Bacillus cereus can cause fatal sepsis in an immunocompromised patient. A 51-years-old female with acute myeloid leukemia (M2) received remission-induction therapy. On day +7, moderate fever and diarrhea developed, and cefepime was instituted. Symptoms were improved, and blood culture was negative. However, severe abdominal pain developed on day +15, followed by high fever. Cefepime was changed to meropenem, but she became comatose with rapidly progressing liver dysfunction. She died on day +17. Bacillus cereus was detected from the blood culture on day +16. This isolate was resistant to all types of β-lactams, but did not produce metallo-β-lactamase. |
| Keywords |
Bacillus cereus, fulminant, sepsis, leukemia |
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