 |
The Journal of the Japanese Society for Clinical Microbiology |
Biblioraphy Information
| ArticleTitle |
A Case of Disseminated Pulmonary Candidiasis Caused by Candida glabrata |
| Language |
J |
| AuthorList |
Toshimori Yamaoka1), Sayoko Kawakami2), Mariko Yamamura1), Ryuichi Fujisaki1), Yasuo Ono3), Hajime Nishiya1) |
| Affiliation |
1) Department of Internal Medicine, Teikyo University School of Medicine
2) Department of Central Laboratory, Teikyo University Hospital
3) Department of Microbiology and Immunology, Teikyo University School of Medicine |
| Publication |
J.J.C.M.: 17 (2), 124-130, 2007 |
| Received |
March 14, 2007 |
| Accepted |
March 23, 2007 |
| Abstract |
Twenty-seven year old woman was admitted to our surgical department because of abdominal pain. Several days after an insertion of a central venous catheter she had a candidemia, followed by disseminated lesions in the both lungs of candidiasis 2 weeks-after. The high levels of serum (1→3)β-D-glucan, two times of episodes of Candida glabrata from blood and localized lesions in the lung with no other foci evaluated with radiological findings supported her disseminated candidiasis localized in both lungs, the candidiasis localized in the lungs by Candida glabrata being the first reported case in Japan. After a removal of the catheter, administration of fluconazol brought defervescence, but the serum levels of the β-D-glucan and the disseminated lesions showed little improvement, which improved after administration of amphotericin B. Many cases with disseminated candidiasis were diagnosed after their death. The serum levels of the glucan and radiological evaluation present useful information in diagnosing and monitoring the disseminated candidiasis. |
| Keywords |
disseminated candidiasis, amphotericin B, fluconazole |
|
