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The Journal of the Japanese Society for Clinical Microbiology |
Biblioraphy Information
| ArticleTitle |
Surveillance of Blood Culture Results from Cancer Patients: Five-year Experience in National Cancer Center Hospital |
| Language |
J |
| AuthorList |
Hiroko Ito, Shinichiro Mori, Akiko Higuchi, Koji Ono, Nobuhiko Kurano, Koh Furuta |
| Affiliation |
Clinical Laboratory, National Cancer Center Hospital, 5-1-1 Tsukiji, Chuo-ku Tokyo 104-0045, Japan |
| Publication |
J.J.C.M.: 17 (4), 284-289, 2007 |
| Received |
March 26, 2007 |
| Accepted |
October 7, 2007 |
| Abstract |
We retrospectively surveyed blood culture results from 2001 to 2005 at National Cancer Center Hospital. 2,625 strains out of 24,187 specimens were isolated, and overall positive rate was 9.0%. In these strains, 969 ( 36.9%) were gram-negative bacteria, 1,100 (41.9%) were gram-positive cocci, 122 (4.6%) were anaerobic bacteria, 94 (3.5%) were fungi, and 340(13.0%) were others. Among 969 gram-negative strains, the most common species was Escherichia coli, which consisted of 202 (20.8%) strains. In 1,100 strains of gram positive cocci, 600 (54.5%) were coagulase-negative staphylococci (CNS), and 130(11.8%) were methicillin-resistant Staphylococcus aureus (MRSA). In other bacteria, Bacillus spp. was 78.9% and coryne form bacteria was 16.7%. 52 strains of coryne form bacteria were isolated from 27 cases, and almost all (49 strains, 94.2%) the strains were isolated from the patients with hematologic malignant disorders (including the patients undergoing hematopoietic stem cell transplantation) or pediatric patients maladies. Among 27 patients with coryne form bacteria, 22 patients (81.5%) were diagnosed as highly immunocompromised conditions. In cases of coryne form bacteria, the identification of species was often difficult by only with commercially available identification kits. Therefore, nucleic-acid based identification by sequencing of 16S RNA is necessary in cancer center such as our institution. |
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