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The Journal of the Japanese Society for Clinical Microbiology |
Biblioraphy Information
| ArticleTitle |
A Case of Pulmonary Chromomycosis Caused by Exophiala dermatitidis |
| Language |
J |
| AuthorList |
Chiyoko Tanamachi, Kouji Hashimoto, Kazunori Nakata, Kimitaka Sagawa |
| Affiliation |
Department of Laboratory Medicine, Kurume University Hospital |
| Publication |
J.J.C.M.: 18 (1), 25-30, 2008 |
| Received |
March 29, 2007 |
| Accepted |
January 9, 2008 |
| Abstract |
We report a rare case of pulmonary mycosis involving E. dermatitidis. The subject was a 53-year-old woman with a history of bronchiectasis whose primary complaints at the time of hospitalization were yellowish phlegm and anterior chest pain. Chest X-rays and chest CT images revealed a shadow in the lower right lung field, and pulmonary mycosis was suspected. Grocott staining of samples from the patient's bronchial lavage fluid showed many yeast-like fungi. When coughed up sputum and bronchial lavage fluid were cultured at 35°C, colonies formed which appeared to be black yeast. However, when cultured at 27°C filamentous colonies formed, so we confirmed a diagnosis of the dimorphic black yeast Exophiala dermatitidis. After initial treatment with miconazole, combined treatment with itrazonazole and flucytosine proved effective. |
| Keywords |
Exophiala dermatitidis, dematiaceous fungi, pulmonary chromomycosis |
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