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The Journal of the Japanese Society for Clinical Microbiology |
Biblioraphy Information
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[Vol.18 No.2 contents] Japanese / English |
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| ArticleTitle | Study on IMP-type Metallo-β-lactamase-producing Glucose-non-fermentative Gram-negative Bacteria Isolated from Three Hospitals in Aichi Prefecture |
| Language | J |
| AuthorList | Atsuko Matsunami1), Toshi Nada2), Hiroko Tsuchiya3), Ryoichi Takeda1), Nobuko Sato3), Hisashi Baba2),4), Naohiro Shibata5), Yoshichika Arakawa5) |
| Affiliation |
1) Department of Clinical Laboratory, Nishio Municipal Hospital 2) Department of Clinical Laboratory, Nagoya University Hospital 3) Department of Clinical Laboratory, Ichinomiya Municipal Hospital 4) Department of Infectious Diseases, Nagoya University Hospital 5) Department of Bacterial Pathogenic and Infection Control, National Institute of Infection Diseases |
| Publication | J.J.C.M.: 18 (2), 100-108, 2008 |
| Received | June 8, 2007 |
| Accepted | April 23, 2008 |
| Abstract | We isolated three species of IMP-1 metallo-β-lactamase (MBL)-producing glucose-nonfermentative gram-negative bacteria at three hospitals (Acinetobacter baumannii from 3 patients in a surgical ward at Hospital A, Pseudomonas putida from 5 in a hematological ward at Hospital B, and Alcaligenes xylosoxidans from 4 in a urological ward at Hospital C, respectively) in Aichi Prefecture from May 2002 to September 2003. Drug susceptibilities were tested, and MBL productivity using a disk diffusion test, IMP-1 gene detection by PCR, and pulsed-field gel electrophoresis (PFGE) were performed. All 24 strains, in total, produced IMP-1 type MBL, and showed multi-drug resistance. All strains from each patient showed the same pattern in PFGE. In addition, all strains belonging to each single species, with the exception of A. baumannii from one of the three patients, also showed the same pattern in PFGE. Most of the patients had some of the common risk factors including underlying diseases, operations, medical devices and long periods of hospitalization. The frequencies for isolating these glucose-nonfermentative gram-negative bacteria are relatively low for the moment. However, due precautions should be taken, since they might colonize in a ward over a long period. |
| Keywords | Acinetobacter baumannii, Pseudomonas putida, Alcaligenes xylosoxidans, IMP-1 |
| Copyright © 2002 The Japanese Society for Clinical Microbiology All rights reserved. |