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The Journal of the Japanese Society for Clinical Microbiology |
Biblioraphy Information
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[Vol.18 No.3 contents] Japanese / English |
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| ArticleTitle | A Case of Multiple Osteomyelitis Due to Mycobacterium avium in an Non-AIDS Patient |
| Language | J |
| AuthorList | Harumi Oguchi1), Toshio Sato2), Takefumi Suzuki3), Shinya Houkibara4), Masahiko Shimomura4), Eriko Kasuga3), Takehisa Matsumoto3), Eiko Hidaka3), Yoshiyuki Kawakami5), Kazuo Morozumi1), Tsutomu Hachiya6) |
| Affiliation |
1) Department of Laboratory Medicine, Suwa Red Cross Hospital 2) Department of Cardiology, Suwa Red Cross Hospital 3) Department of Laboratory Medicine, Shinshu University Hospital 4) Department of Pathology, Suwa Red Cross Hospital 5) Department of Biomedical Laboratory Sciences, School of Health Sciences, Shinshu University School of Medicine 6) Department of Respiratory, Suwa Red Cross Hospital |
| Publication | J.J.C.M.: 18 (3), 193-198, 2008 |
| Received | January 30, 2008 |
| Accepted | June 13, 2008 |
| Abstract | Non-tuberculous mycobacteria are known to cause opportunistic infectious diseases in immunocompromised patients. We encountered a case of disseminated non-tuberuculous mycobacteriosis due to Mycobacterium avium. Patient was a 46 year-old woman who was transferred to our hospital because of conspicuously abnormal high-intensity area on lumbar vertebrae by means of MRI scanning examination. Her chief complaints were fever, cervical lymphadenopathy, and low back pain. She was evident of progressive cervical lymphadenopathy and myelitis, and therefore was suspected of a bone marrow disease, metastatic carcinoma, connective tissue diseases, and tuberculosis. Finally, she was diagnosed as multiple osteomyelitis by the successful detection of M. avium from her iliac bone marrow fluid and biopsy of right iliac bone and 5th lumbar vertebra. She was demonstrated to be negative in both HIV and HTLV-1 antibody tests, and demonstrated to possess no indicative sign of immunodeficiency. She was treated in outpatient clinic with combined administration of three anti-tuberculous drugs comprising of ethambtol, kanamycin, rifampicin, together with clarithromycin. The extrapulmonary infection with M. avium has rarely been described. This was an infrequent case of disseminated M. avium infection, occurred in a non-AIDS female patient lacking in immunodeficiency. |
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| Copyright © 2002 The Japanese Society for Clinical Microbiology All rights reserved. |