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The Journal of the Japanese Society for Clinical Microbiology |
Biblioraphy Information
| ArticleTitle |
The Analysis of Levofloxacin-resistant Esherichia coli Isolated from the Patients of Urinary Tract Infections and Their Background Factors |
| Language |
J |
| AuthorList |
Ken-ichi Ogura, Fuyuhiko Saito, Akira Turuoka, Ikuo Saito |
| Affiliation |
Department of Clinical Laboratory, Tama-Nambu Chiiki Hospital |
| Publication |
J.J.C.M.: 18 (4), 221-226, 2008 |
| Received |
March 14, 2008 |
| Accepted |
August 1, 2008 |
| Abstract |
The objective of this study is to investigate the prevalence of levofluxacin (LVFX) resistant Escherichia coli, its drug-resistance pattern, and the background factors on resistant bacteria isolation for Escherichia coli isolated from urine specimens of the patients visited outpatient department of Urology, Tama-Nanbu Chiiki Hospital for 5 years from January 2001 to December 2005. As the regional medical support hospital for 5 cities in Tama region, this hospital is the secondary medical institute and mainly accepts referral patients by registered physicians. 125 strains of Escherichia coli out of total 811 testing specimens were isolated and 27 strains among them were found to be LVFX-resistant (MIC: ≥4 μg/ml) It was shown that resistant bacteria were gradually increased year by year and LVFX resistant bacteria, even in the community, were also increasing. The analysis of patients background factors statistically clarified that the patients with chronic diseases and the history of prior administration of quinolone drug had the tendency to be easily affected urinary tract infection due to LVFX resistant Escherichia coli.
In conclusion, the microbiology laboratory at a general hospital assuming medical treatment for the specific region should always grasp the trend of bacterial resistance of oral antibiotics frequently used at the primary medical institute and give feedback those results as the infectious information. At the same time, we feel obligated to monitor and control the isolation status of resistant strains in the whole region. |
| Keywords |
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