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The Journal of the Japanese Society for Clinical Microbiology |
Biblioraphy Information
| ArticleTitle |
Increasing two-sets blood cultures and its efficacy |
| Language |
J |
| AuthorList |
Yumiko Tanimichi, Michiko Yagoshi, Mitsuru Yanai, Yuki Uehara, Naoto Hosokawa, Kazuo Shimoguchi, Hiroko Yamada, Mutsuko Oosoko, Sachiyo Yamamoto, Kazunari Kumasaka |
| Affiliation |
1) Clinical Laboratory Nihon University Itabashi Hospital
2) Department of Laboratory Medicine, Nihon University School of Medicine
3) Department of Infection Control Science, Faculty of Medicine, Juntendo University
4) Department of Infectious Disease, Kameda General Hospital |
| Publication |
J.J.C.M.: 18 (4), 245-251, 2008 |
| Received |
March 24, 2008 |
| Accepted |
August 18, 2008 |
| Abstract |
Importance of multi-sets blood cultures is indicated so as to increase the positivity rate and help clinical judgment. But in Japan, the importance has not been recognized yet because multiple sets of blood cultures are troublesome and induce an increase in costs. In our hospital, we have encouraged to take two sets of blood cultures. As a result, the percentage of two-sets blood cultures increased from 21.0% in 2001 to 59.0% in 2004. The total positivity rate of two-sets blood cultures (22.1%) was significantly higher than that of one-set blood culture (14.0%, p<0.01). Regarding the isolates, only one of two sets showed positive results in 31.3% of the family Enterobacteriaceae, 41.9% of Non-fermentative Gram-negative rods and 21.4% of Staphylococcus aureus, which should be the pathogens of bacteremia when they are isolated in blood cultures. On the other hand, coagulase-negative Staphylococci, which is frequently recognized as contamination, 74.8% was positive in only one of two sets. In conclusion, two-sets blood cultures are useful to increase the positivity rate of blood culture significantly. Large percentage of essential pathogens can be detected by only one of two sets, and they also help for the interpretation of positive results of coagulase-negataive Staphylococci usually recognized as contaminant. |
| Keywords |
cultivation of blood, two-sets blood culture, detection rate of germ |
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