Journal

The Journal of the Japanese Society for Clinical Microbiology

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[Vol.19 No.3 contents]
Japanese / English

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Article in Japanese

ArticleTitle A Case of Brain Abscess caused by Nocardia asiatica
Language J
AuthorList Ayumi Ryu1), Ryuji Kawahara2), Kosuke Mori3), Masakazu Tamura3), Kyoko Nakano1), Ayako Yoshioka1), Masako Ayaki1), Koji Tomita1), Tomoyuki Yamasaki1), Satiko Tanaka1), Motohiko Maruno3), Katsukiyo Yazawa4), Yuzuru Mikami4)
Affiliation 1) Laboratory of Medicine, Osaka Medical Center for Cancer and Cardiovascular Diseases
2) Division of Bacteriology, Department of Infectious Diseases, Osaka Prefectural Institute of Public Health
3) Department of Cerebral Nerve Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases
4) Medical Mycology Research Center, Chiba University
Publication J.J.C.M.: 19 (3), 163-170, 2009
Received February 29, 2008
Accepted April 28, 2009
Abstract Nocardia asiatica was established as a new species within the genus of Nocardia in 2004. We report a case of brain abscess caused by N. asiatica. It was identified as N. asiatica by 16S rRNA gene sequencing. Sulfamethoxazole/trimethoprim (ST) and imipenem/cilastatin (IPM/CS) was administered to the pacient by susceptility test. But symptoms did not improved. Because of fever to last and chest abnormality shadow, medicine-related pneumonia was suspected. ST and IPM/CS were changed to minocycline (MINO). The patient restored afterward, who continued taking oral MINO for one year. Then it does not recur. Reports of new species of Nocardia are increasing recently. To clarify characteristics of infection by new species is objective in the near future.
Keywords Nocardia asiatica, brain abscess, 16S rRNA gene, minocycline
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