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The Journal of the Japanese Society for Clinical Microbiology |
Biblioraphy Information
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[Vol.20 No.1 contents] Japanese / English |
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| ArticleTitle | A Case of Rothia mucilaginosa (Stomatococcus mucilaginosus) Bacteremia in a Patient with Acute Myelocytic Leukemia and Evaluation of the Ability to Identify for This Organism Used Identification Kits |
| Language | J |
| AuthorList | Yoko Fukugawa1,2), Mitsuhiro Okazaki1), Kiyofumi Ohkusu3), Hiroyuki Nishiyama4), Yoshimi Higurashi5), Ayako Tanouchi1), Takahiro Okuyama1), Shota Yonetani1), Hiroshi Makino1), Noriko Sawada1), Koji Araki1), Nobuyuki Takayama6), Takayuki Ezaki3), Hiroaki Ohnishi7), Takashi Watanabe1,7) |
| Affiliation |
1) Laboratory of Medicine, Kyorin University School of Medicine 2) Department of Microbiology and Immunology, Graduate School of Health Care Sciences, Tokyo Medical and Dental University 3) Department of Microbiology, Regeneration and Advanced Medical Science, Gifu University Graduate School of Medicine 4) Central Clinical Laboratories, Surugadai Nihon University Hospital 5) Department of Infection Control and Prevention, University of Tokyo Hospital 6) Second Department of Internal Medicine, Kyorin University School of Medicine 7) Department of Laboratory Medicine, Kyorin University School of Medicine |
| Publication | J.J.C.M.: 20 (1), 50-55, 2010 |
| Received | October 9, 2009 |
| Accepted | December 14, 2009 |
| Abstract | Rothia mucilaginosa is found in the oral cavity and pharynx of man where it forms part of the normal microflora. This organism is also recognized as an opportunistic pathogen causing bacteremia, meningitis and pneumoniae. We report the first case of bacteremia caused by R. mucilaginosa in Japan. A 68-year-old male with acute myeloid leukemia received gemtuzumab ozogamicin therapy. The patient had signs of oral mucositis, and R. mucilaginosa was isolated from blood cultures during prophylactic ciprofloxacin. We also evaluated the ability of the following kits to identify R. mucilaginosa: PMIC/ID-35, PC.6.1B, GPI card, API STAPH, API Coryne, rapid ID 32 STREP and N-IDtestSP-18. PMIC/ID-35 and GPI card could identify this organism, because they had its bacterial code. PC.6.1B could not identify it, and another kit misidentified it as other gram positive organisms. This study illustrates the possible virulence of R. mucilaginosa in immunocompromised host with oral mucositis, and indicates that this organism may be misidentified in the currently used commercial kits. |
| Keywords | Rothia mucilaginosa, Stomatococcus |
| Copyright © 2002 The Japanese Society for Clinical Microbiology All rights reserved. |