 |
 |
 |
The Journal of the Japanese Society for Clinical Microbiology |
Biblioraphy Information
|
[Vol.21 No.3 contents] Japanese / English |
|
| ArticleTitle | A Study of Metallo-β-Lactamase-Producing Klebsilla pneumoniae from Neonatal Intensive Care Unit |
| Language | J |
| AuthorList | Kohta Katsuki1,2), Zenzo Nagasawa3), Teturo Muratani4,5) |
| Affiliation |
1) Deparment of Clinical Laboratory, National Hospital Organization, Kumamoto Medical Center 1 2) Deparment of Clinical Laboratory, National Hospital Organization, Saga Hospital 3) Depatment of Clinical Laboratory, Saga University Hospital 4) Kyurin Corporation 5) Department of Urology, School of Medicine, University of Occupational and Environmental Health |
| Publication | J.J.C.M.: 21 (3), 185-192, 2011 |
| Received | August 27, 2010 |
| Accepted | May 9, 2011 |
| Abstract | We experienced a case which is suspected to be a hospital infection of Metallo-β-lactamase (MBL)-producing Klebsiella pneumoniae. The patient who became an origin of the infection is a girl whose birth weight was 539 g. On the 46 days of age she fell into the shock with the decline of SpO2, abdominal distension and bloody stool. Under a diagnosis of necrotizing enterocolitis, the necrotic colon was removed and the artifical anus was made. This infection could not be controlled by medication of ceftazidim, vancomycin, or cefotaxime but by medication of meropenem, and her life was saved. IMP-1 type MBL-producing K. pneumoniae were isolated from the culture of her blood, ascites and stool. Because the MBL-producing K. pneumoniae were also isolated from two other infant, the hospital infection was suspected, and the stool culture was proceeded from all of the infants in this ward. Consequently the K. pneumoniae which was isolated from the 6 infants including the 3 infants above and the same electrophoretic pattern was obserbed by PFGE analysis. The prevention of contact infection was carried out, but the MBL-producing K. pneumoniae were isolated from 13 infants finally. Because the immune sysytem of prmature infants are immature, the spread of antibiotics resistant bacteria is a very serious problem. Careful monitorings of the antibiotics resistant bacterias are needed in Neonatal intensive care unit. |
| Keywords | Klebsiella pneumoniae, meropenem |
| Copyright © 2002 The Japanese Society for Clinical Microbiology All rights reserved. |