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The Journal of the Japanese Society for Clinical Microbiology |
Biblioraphy Information
ArticleTitle |
Identification of Rhizomucor variabilis Isolated from a Bile Sample of a Cancer Patient |
Language |
J |
AuthorList |
Kenji Irimura1), Shuichi Nonaka1), Yuka Miyazoe2), Kazuko Nishimura3) |
Affiliation |
1) Clinical Laboratory and 2) Division of Internal Medicine, National Hospital Organization, Saga Hospital
3) Department of Microbiology, Dokkyo Medical University School of Medicine and First Laboratories Co., Ltd.
* Present affiliation: Japanese Red Cross Nagasaki Genbaku Isahaya Hospital |
Publication |
J.J.C.M.: 21 (4), 260-269, 2011 |
Received |
June 1, 2011 |
Accepted |
August 9, 2011 |
Abstract |
A bile sample taken from an icteric patient with renal cancer by percutaneous transhepatic cholangio-drainage was cultured using several isolation media. A mucoralean zygomycete and Candida albicans were cultured together with two bacterial species. The zygomycete produced diverse sporangiospores in shapes and sizes, and large chlamydospores. Maximum growth temperature was 38°C. These findings coincided with Rhizomucor variabilis and the sequence on the ITS region was 100-99% identical with the species. The bile smear showed broad hyphae and large chlamydospores on HE and PAS preparations with pseudohyphae and budding spores of Candida sp. Although R. variabils is mainly isolated from cutaneous zygomycosis in China, to our knowledge, this is the first isolation from internal organ samples throughout the world. |
Keywords |
Rhizomucor variabilis |
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