Journal

The Journal of the Japanese Society for Clinical Microbiology

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[Vol.24 No.1 contents]
Japanese / English

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Article in Japanese

ArticleTitle A case of Streptococcal Toxic Shock-like Syndrome suspected of originating from external genital infection
Language J
AuthorList Akifumi Nakayama1), Akiko Nagae1), Kouji Ui1), Akira Koizumi1), Yoshio Uchiike1), Kazunobu Norimoto2)
Affiliation 1) Department of Clinical Laboratory, Nara Medical University Hospital
2) Department of Emergency and Critical Care Medicine, Nara Medical University
Publication J.J.C.M.: 24 (1), 41-46, 2014
Received September 9, 2013
Accepted February 4, 2014
Abstract Among the various types of necrotizing fasciitis, infection with Streptococcus pyogenes (S. pyogenes) occurs in patients without underlying diseases, leading to the rapid progression of tissue necrosis. In this study, we report a patient with fulminant S. pyogenes infection related to the adult-entertainment business (oral sex). Concerning the bacteriological profiles of an isolated strain, the emm type was evaluated as emm 89.14, and Streptococcal pyrogenic exotoxin genes, speB, speC, speG, and speF, were present. The patient was healthy, and his medical history (other than vertigo) was not contributory. There were no factors involved in reduced immunity, such as diabetes, HIV infection, or steroid therapy. Therefore, the fulminant condition in the present case may have been related to the virulence factors of the isolated strain, Streptococcus pyogenes.
Keywords Streptococcus pyogenes, Streptococcal pyrogenic exotoxin
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