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The Journal of the Japanese Society for Clinical Microbiology |
Biblioraphy Information
| ArticleTitle |
The state of isolation and antimicrobial susceptibility of ampicillin resistant Haemophilus influenzae detected in our hospital |
| Language |
J |
| AuthorList |
Mina Fukuoka, Hitoshi Miyamoto, Shinobu Murakami, Mari Morimoto, Yuri Tanaka, Tatsuya Nishimiya |
| Affiliation |
Department of Clinical Laboratory, Ehime University Hospital |
| Publication |
J.J.C.M.: 24 (3), 213-219, 2014 |
| Received |
March 20, 2014 |
| Accepted |
June 26, 2014 |
| Abstract |
We studied three things regarding Haemophilus influenzae that was isolated at Ehime University Hospital, (1) a comparison of the state that ampicillin resistant strains were detected, (2) an alteration of the isolating rate about strains that produce β-lactamase, and (3) the latest antimicrobial susceptibility. As for (1), β-lactamase producing amoxicillin/clavulanic acid resistant (BLPACR-II) and β-lactamase nonproducing ampicillin resistant (BLNAR) increased about 10%, Low-BLNAR, β-lactamase nonproducing ampicillin resistant (BLNAS) and -lactamase producing ampicillin resistant (BLPAR) each decreased 10, 5, 3%. Especially, the increase was remarkable for BLNAR derived from inpatients and BLPACR-II derived from outpatients. As regards (2), the isolating rate had increased 1995 to 1997, and after it reached the peak in 1997, had decreased for few years. But in recent years, it showed an increasing tendency again. From (3), while ampicillin was effective in half of all strains and sulbactam/ampicillin was in 80%, the sensitivity of tazobactam/piperacillin, ceftriaxone and meropenem was doing very well. It suggested that these three drugs are effective as curative. MICs of levofloxacin and ciprofloxacin were low readings, but we observed that two strains were so tolerant. |
| Keywords |
Haemophilus influenzae, ftsI |
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