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The Journal of the Japanese Society for Clinical Microbiology |
Biblioraphy Information
| ArticleTitle |
Characterization of small-colony variant of Serratia marcescens isolated from a patient with pulmonary aspergilloma |
| Language |
J |
| AuthorList |
Yusuke Ota1), Takehisa Matsumoto2), Eriko Kasuga2), Kazuki Horiuchi2), Tatsuya Negishi2), Tomomi Yaguchi2), Tatsuya Natori2) |
| Affiliation |
1) Department of Health and Medical Sciences, Shinshu University, Nagano, Japan
2) Department of Laboratory Medicine, Shinshu University Hospital, Nagano, Japan |
| Publication |
J.J.C.M.: 25 (2), 125-130, 2015 |
| Received |
September 4, 2014 |
| Accepted |
November 21, 2014 |
| Abstract |
Serratia marcescens small-colony variant (SCV), which showed atypical colony morphology, was isolated from the sputum and lung tissue of a patient with pulmonary aspergilloma. Non-fermentation of glucose was determined with triple sugar iron agar slant. However, MicroScan WalkAway 96 Plus System identified the isolate as Yersinia enterocoritica group. The isolate was identified as S. marcescens by sequence analysis of the 16S rRNA gene and MALDI Biotyper system. Although S. marcescens is known to have natural resistance to various antibiotics, current isolate was susceptible to ampicillin, amoxicillin/clavulanic acid, cefaclor, cefmetazole and colistin by the broth microdilution or disk diffusion method. S. marcescens SCV made it difficult to obtain reliable results in antimicrobial susceptibility test. The bacterial identification of SCV is important for selection of effective antibiotics. |
| Keywords |
Small Colony Variants, Serratia marcescens, 16S rRNA, MALDI Biotyper |
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