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The Journal of the Japanese Society for Clinical Microbiology |
Biblioraphy Information
| ArticleTitle |
A household transmission of hepatitis A |
| Language |
J |
| AuthorList |
Chiyoko Motegi1), Kentaro Kikuchi1,2), Michiko Nagai1), Suzuko Ashikawa1), Yusuke Kajiyama2), Atsuko Takai2), Hiroshi Miyakawa2), Takako Misaki3), Hideaki Shimizu3), Nobuhiko Okabe3), Minoru Yoshida2) |
| Affiliation |
1) Infection Control Team, Teikyo University Mizonokuchi Hospital
2) The Fourth Department of Internal Medicine, Teikyo University Mizonokuchi Hospital
3) Kawasaki City Institute for Public Health |
| Publication |
J.J.C.M.: 25 (3), 230-233, 2015 |
| Received |
August 18, 2014 |
| Accepted |
February 19, 2015 |
| Abstract |
We have experienced the onset case of type A hepatitis among family members. The patient was female at age of 45 and her husband already had hepatitis A 10 weeks ago. The patient's symptom was improved without becoming severe and her hepatitis A viral genotype was IA. Four weeks after her admission, HAV-RNA was found in feces of her son at age of 5, but he had no symptom. It was matched 100% with the patient for DNA sequence of VP1/2A area. We have confirmed it as negative after we conducted the fecal examination every two weeks for her son.
It needs to be carefully monitored for intrafamilial transmission because antibody retention ratio has been declining due to a lowering of hepatitis A prevalence rate in Japan. |
| Keywords |
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