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The Journal of the Japanese Society for Clinical Microbiology |
Biblioraphy Information
| ArticleTitle |
A pneumonia case by multiple pathogens including Mycobacterium septicum |
| Language |
J |
| AuthorList |
Osam Kobayashi1), Kinuyo Morita1), Yuko Kazumi2), Shingo Muramoto3) |
| Affiliation |
1) Department of Clinical Laboratory, Noto General Hospital
2) Molecular Epidemiology and Genetic Identification Division, Department of Mycobacteria References and Research, Research Institute of Tuberculosis, Japan Anti-Tuberculosis Association
3) Internal Medicine, Noto General Hospital |
| Publication |
J.J.C.M.: 26 (2), 124-130, 2016 |
| Received |
September 3, 2015 |
| Accepted |
November 19, 2015 |
| Abstract |
Case report; A 87 years-old female patient had fever at 37.7°C and general fatigue on October 10, 2011. She visited a physician and was pointed out abnormal infiltration on the right lung field on chest X-way, and was referred to Noto General Hospital on November 2nd. She had a history of pulmonary tuberculosis (clinically cured), diabetes mellitus (borderline), hypertension, dyslipidemia, and chronic heart failure. The chest CT showed infiltration (pneumonia) in the right lower lobe. With respiratory aspiration specimen, several bacterial strains including Streptococcus pneumoniae, Streptococcus agalactiae, anaerobic bacteria, and acid-fast bacilli (AFB) growing on 2% Ogawa medium in 3 days were isolated. The AFB was considered as rapid growing mycobacterium but not identified by using DNA-DNA hybridization method. The strain was identified as Mycobacterium septicum by DNA sequencing of 16S rRNA, rpoB and hsp65, with growth temperature test and sugar (mannitol, inositol and sorbitol) assimilation test. The patient improved clinically and the infiltration disappeared at most with ceftriaxone treatment. M. septicum showed the MIC of >32 μg/ml against cefotaxim. M. septicum might play an role as an infectious agent in this case, and had a chance of microbial substitution because it was resistant to the antibiotic. Then, the description of characteristic of M. septicum will have clinical importance. |
| Keywords |
Mycobacteriumsepticum |
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