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The Journal of the Japanese Society for Clinical Microbiology

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[Vol.27 No.2 contents]
Japanese / English

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Article in Japanese

ArticleTitle Familial infection caused by Salmonella enterica subsp. enterica serovar Paratyphi A with low sensitivity to fluoroquinolone: a case report
Language J
AuthorList Akari Sakai1), Kana Sawada1), Masumi Taguchi2)
Affiliation 1) Department of Central Laboratory, Minoh Municipal Hospital
2) Osaka Prefectural Institute of Public Health
Publication J.J.C.M.: 27 (2), 88-96, 2017
Received June 22, 2016
Accepted January 20, 2017
Abstract In February 2012, a 2-year-old male (first child) presented to our hospital with prolonged high fever after an influenza infection. Blood culture revealed the growth of Salmonella enterica subsp. enterica serovar Paratyphi A colonies. As a result of an intrafamilial stool test, S. Paratyphi A was identified in the stool of his father, who regularly travelled to India. Two months later, his grandfather presented with high fever, diarrhoea and bloody stool. Stool culture revealed the growth of S. Paratyphi A colonies. We analysed the strains originating from the three infected people using various epidemiological markers; all strains were identical and this was speculated to be a case of familial infection. All isolates of this case had low sensitivity to fluoroquinolone; many such bacteria have been reported in Southern Asia. In order to carry out appropriate treatment, global trends in the appearance of drug-resistant bacteria should be taken into account. If a patient presents to the hospital with a typhoid fever-related symptoms, a familial infection, as in the present case, should be considered, and testing and sanitization treatment should be done to prevent further spread.
Keywords Salmonella enterica subsp. enterica serovar Paratyphi A
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