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The Journal of the Japanese Society for Clinical Microbiology |
Biblioraphy Information
| ArticleTitle |
The Performance of the Verigene CDF Panel in the Molecular Identification of Toxigenic Clostridium difficile in Stool Samples |
| Language |
J |
| AuthorList |
Yuji Yaguchi1), Atsuo Ueda2), Koji Nakamura2), Kiyoko Tamai1), Hiromichi Suzuki3) |
| Affiliation |
1) Miroku Medical Laboratory Inc.
2) Department of Clinical Laboratory, Tsukuba Medical Center Hospital
3) Division of Infectious Diseases, Department of Medicine/Department of Clinical Laboratory Medicine, Tsukuba Medical Center Hospital |
| Publication |
J.J.C.M.: 27 (3), 188-194, 2017 |
| Received |
January 23, 2017 |
| Accepted |
March 21, 2017 |
| Abstract |
We prospectively evaluated the performance of the Verigene CDF panel, C. DIFF QUIK CHEK COMPLETE and Xpect Clostridium difficile Toxin A/B Test in May 2015 and August 2016. Forty-three of 107 stool samples were positive for glutamate dehydrogenase (GDH) and 35 were positive for toxigenic C. difficile. The positive concordance rate and negative concordance rate of the C. DIFF QUIK CHEK COMPLETE were 57% and 99%, respectively, while the positive concordance rate and negative concordance rate of the Xpect Clostridium Difficile Toxin A/B Test were 49% and 99%. In contrast, the Verigene CDF panel showed a positive concordance rate of 97% and a negative concordance rate of 100%. The Verigene CDF panel reliably detects toxigenic C. difficile in stool samples. It was considered highly valuable-especially in the immunochromatographic assays of GDH-positive and toxin-negative of stool samples. |
| Keywords |
Clostridium difficile, Verigene |
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