 |
The Journal of the Japanese Society for Clinical Microbiology |
Biblioraphy Information
| ArticleTitle |
Phenotypic screening methods for the detection of carbapenemase-producing Enterobacteriaceae |
| Language |
J |
| AuthorList |
Kageto Yamada1), Noriyuki Nagano2), Ryoichi Saito3) |
| Affiliation |
1) Department of Clinical Laboratory, Tokyo Metropolitan Health and Medical Treatment Corporation Toshima Hospital
2) Department of Health and Medical Science, Graduate School of Medicine, ShinShu University
3) Department of Microbiology and Immunology, Graduate of Health Care Science, Tokyo Medical and Dental University |
| Publication |
J.J.C.M.: 27 (4), 267-274, 2017 |
| Received |
July 18, 2017 |
| Accepted |
|
| Abstract |
Carbapenems are used as last resort treatment of antimicrobial-resistant pathogens. Nevertheless, the increase of plasmid-mediated β-lactam-resistant pathogens, including carbapenemase-producing Enterobacteriaceae (CPE), is a major concern worldwide. Therefore, highly sensitive and specific methods for CPE detection in clinical laboratory setting are critical. In this review, we provide an overview of the currently available screening methods without molecular methods for the detection of CPE. |
| Keywords |
Carbapenemase-producing Enterobacteriaceae, modified Hodge test, carba NP test, carbapenem inactivation method |
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